Akathisia

From Anvita Health Wiki

Contents 1 Introduction 2 Etiology 3 Clinical-manifestations 4 Management 5 More General Terms 6 Additional Terms 7 References

Introduction

• A state of distressing inner restlessness

Etiology

• chronic neuroleptic administration
• antiemetics - metoclopramide
• dyskinetic movement disorder

Clinical-manifestations

• uncomfortable mental & physical restlessness
• inability to sit still

Management

• discontinue offending agent if possible
• treated like drug-induced parkinsonism
• substituting antipsychotic for one with more anticholinergic activity

• trihexyphenidyl ( Artane)
• diphenhydramine

• midazolam more effective but more sedating than diphenhydramine

More General Terms

• sign/symptom

Additional Terms

• drug-induced parkinsonism
• restless legs syndrome (RLS)

References

1. Harrison's Online, McGraw-Hill, 2002
2. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
3. Parlak I et al Midazolam vs diphenhydramine for the treatment of metoclopramide-induced akathisia: A randomized controlled trial. Acad Emerg Med 2007, 14:715 PMID: [1]

akathisia