Age Related Physiological Changes
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Contents |
More Specific Terms
- age-associated changes in adipose tissue
- age-associated changes in cardiovascular function
- age-associated changes in hearing
- age-associated changes in hematopoiesis
- age-associated changes in immunity
- age-associated changes in pulmonary function
- age-associated changes in renal function
- age-associated changes in skeletal muscle
- age-associated changes in sleep
- age-associated changes in smell
- age-associated changes in teeth
- age-associated changes in temperature regulation
- age-associated changes in the autonomic nervous system
- age-associated changes in the central nervous system
- age-associated changes in the digestive system
- age-associated changes in the endocrine system
- age-associated changes in the eye
- age-associated changes in the peripheral nervous system
- age-associated changes in the reproductive system
- age-associated changes in the skeletal system
- age-associated changes in the urinary system
- age-associated changes in the vestibular system
- age-associated changes in thirst
- neuropsychiatric features of aging
- pharmacokinetics in the elderly
- skin aging (includes aging of skin appendages)
Introduction
- # General
- diminished ability to maintain homeostasis
- stress-induced changes more marked than changes at rest
- variability increases among individuals
- body size & composition
- decreased lean/fat body ratio
- decreased height after age 30-40
- increased weight up to age 50 in men, 60 in women, then a decline
- total body water decreases
- diminished bone mass & total body Ca+2
- motor skills
- increased 1/2life of lipid-soluble drugs
- increased peak concentration of hydrophilic drugs
- increased time for drug clearance
- # Central nervous system
- # Peripheral nervous system
- # Pulmonary
- # Cardiovascular
- # Renal
- # Urinary
- # Reproductive
- # Digestive system [8]
- # Hematopoietic system
- # Immune
- # Skeletal muscle
- # Skeletal system
- # Adipose tissue
- # Skin
- # Endocrine
- # Sleep
- # Eye (vision)
- # Hearing
- # Vestibular
- # Smell ( olfactory)
- # Thirst
- # Temperature
More General Terms
Additional Terms
- age-related endocrinopathy
- biology of aging
- confounding factors in evaluation of age related changes
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- Mader S: in: Intensive Course in Geriatric Medicine & Board Review, Santa Monica, CA, Sept 20-23, 2000
- Essentials of Clinical Geriatrics, 4th ed, Kane RL et al (eds) McGraw Hill, NY, 1999
- UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
- McPherson, S. Director, Neuropsychology Laboratory UCLA ADRC
- Journal Watch 22(2):17, 2002
- Mader S: UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 25-28, 2002
- Geriatrics Review Syllabus, American Geriatrics Society, 5th edition, 2002-2004
- Steve Castle, Asraf Rafi, personal communication
- Mader S: UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 29-Oct 2, 2004
- Alessi C: UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 29-Oct 2, 2004
- The Merck Manual of Geriatrics, 3rdh ed, Merck & Co, Rahway NJ, 2000
- Taffet GE, Physiology of Aging, In: Geriatric Medicine: An Evidence-Based Approach, 4th ed, Cassel CK et al (eds), Springer-Verlag, New York, 2003
