Adenosine A3 Receptor

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Contents 1 More Specific Terms 2 Function 3 Structure 4 Compartment 5 Alternative-splicing 6 More General Terms 7 Internet Database 8 References

More Specific Terms

• protein ADORA3, isoform 3 (ADORA3-3)

Function

• receptor for adenosine
• activity is mediated by G proteins which inhibit adenylyl cyclase ( Gi proteins)
• role in reproduction ( putative)
• phosphorylation on Ser-317 may play a role in rapid desensitization ( putative)

Structure

• belongs to the G-protein coupled receptor 1 family

Compartment

• cell membrane

Alternative-splicing

• named isoforms=2

More General Terms

• adenosine receptor
• phosphoprotein
• glycoprotein
• receptor
• membrane protein

Internet Database

Kegg: [1]
OMIM: 600445
Prosite: [2]
Prosite: [3]
UniProt: [4]
Entrez gene: 140

References

1. UniProt [5]
2. VanDongen AM, Codina J, Olate J, Mattera R, Joho R, Birnbaumer L, Brown AM. Newly identified brain potassium channels gated by the guanine nucleotide binding protein Go. Science. 1988 Dec 9;242(4884):1433-7. PMID: &dopt=Abstract

adenosine A3 receptor (ADORA3)