Acellular Pertussis Vaccine

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Contents 1 Indications 2 Notes 3 More General Terms 4 Additional Terms 5 References

Indications

• children > 2 years of age, adolescents & adults
• pregnant women, at end of 2nd trimester or in 3rd trimester [4]

Notes

• 92% effective [1]
• effectiveness may diminish within 3 years [5]

More General Terms

• vaccine

Additional Terms

• diphtheria, tetanus toxoid & pertussis vaccine (DPT, DTaP, TDaP, DTP, Acel-Immune, Tri-Immunol, Tripedia, Daptacel, INFANRIX, Adacel, Boostrix)
• diphtheria, tetanus toxoid, pertussis & hemophilus b vaccine (Tetramune, DTP-Hib)

References

1. Ward JI, Cherry JD, Chang SJ, Partridge S, Lee H, Treanor J, Greenberg DP, Keitel W, Barenkamp S, Bernstein DI, Edelman R, Edwards K; APERT Study Group. Efficacy of an acellular pertussis vaccine among adolescents and adults. N Engl J Med. 2005 Oct 13;353(15):1555-63. PMID: [1]
   - Halperin SA. Pertussis--a disease and vaccine for all ages. N Engl J Med. 2005 Oct 13;353(15):1615-7. No abstract available. PMID: [2]
2. Zepp F et al, Safety of reduced-antigen-content tetanus-diptheria acellular pertussis vaccine in adolescents as a sixth consecutive dose of acellular pertussis-containing vaccine. J Pediatr 2006, 149:603 PMID: [3]
   - Haperin SA Recommendation for an adolescent dose of tetanus and diphtheria toxoids and acellular pertussis vaccine: Reassurance for the future. J Pediatr 2006, 149:589 PMID: [4]
3. Prescriber's Letter 14(2): 2007 Adult and Pediatric Immunization Update - 2007 Detail-Document#: [5] (subscription needed) [6]
4. The Washington Post Federal panel recommends vaccinating pregnant women to protect infants from whooping cough [7]
5. Associated Press, Sept 19, 2011 [8]
6. Associated Press: February 22 All older adults added to vaccine advice for whooping cough by US advisory panel Washington Post [9]
7. Centers for Disease Control and Prevention (CDC) Pertussis (Whooping Cough) Vaccination [10]

acellular Pertussis vaccine