Acamprosate

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Contraindications 4 Dosage 5 Adverse-effects 6 Mechanism-of-action 7 Notes 8 More General Terms 9 Internet Database 10 References

Introduction

• Tradename: Campral

Indications

• alcoholism (may be combined with naltrexone)

Contraindications

• renal insufficiency ( creatinine clearance < 30 mL/min)
  

• pregnancy category = c
• safety in lactation = ?

Dosage

• 2 tabs TID

• Tabs: 333 mg enteric coated

Adverse-effects

• headache, diarrhea, flatulence, nausea
  
• drug adverse effects of antipsychotic agents

Mechanism-of-action

• unknown
• thought to favorably modulate the balance between glutamate & GABA

Notes

• Cost = $125/month

More General Terms

• antipsychotic agent

Internet Database

PubChem: 71158
PubChem: [1]
PubChem: [2]
PubChem: [3]
PubChem: [4]

References

1. Prescriber's Letter 12(2): 2005 New Drug: Campral (Acamprosate Calcium) Detail-Document#: [5] (subscription needed) [6]
2. Forest Pharmaceuticals, Inc. www.campral.com

acamprosate (Campral, Alcomed)