1 (2 Choloroethyl) 3 (2 5 Dioxo 3 Piperidyl) 1 Nitrosourea

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Pharmacokinetics 4 More General Terms 5 Internet Database 6 References

Introduction

• Presumptively an alkylating agent by analogy.

Indications

• brain tumors

Pharmacokinetics

• good penetration of the blood-brain barrier

More General Terms

• alkylating agent nitrosourea
• antineoplastic agent (chemotherapeutic agent)

Internet Database

PubChem: 26328

References

Levin et al, Neoplasms of the central nervous system, in: Cancer: Principles & Practice of Oncology, DeVita et al,  eds, Lippincott, Williams & Wilkins, Philadelphia, 2001, pg 2119

1-(2-choloroethyl)-3-(2,5-dioxo-3-piperidyl)-1-nitrosourea (PCNU)